Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination

CONTEXT: Sarcomatous differentiation, which represents transformation to high-grade malignancy, can occur in all histogical types of renal malignancy. CASE REPORT: The authors report on the case of a 66-year-old woman with a right renal mass that was shown to be a clear cell carcinoma. She underwent...

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Main Authors: Alberto Azoubel Antunes, Marcos Francisco Dall’Oglio, José Alexandre Marzagão Barbuto, Kátia Ramos Moreira Leite, Miguel Srougi
Format: Article
Language:English
Published: Associação Paulista de Medicina
Series:São Paulo Medical Journal
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802006000300011&lng=en&tlng=en
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spelling doaj-eb5755a59cc24fc588a8001402bbdcdb2020-11-24T20:41:37ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-9460124316116210.1590/S1516-31802006000300011S1516-31802006000300011Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccinationAlberto Azoubel Antunes0Marcos Francisco Dall’Oglio1José Alexandre Marzagão Barbuto2Kátia Ramos Moreira Leite3Miguel Srougi4Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloCONTEXT: Sarcomatous differentiation, which represents transformation to high-grade malignancy, can occur in all histogical types of renal malignancy. CASE REPORT: The authors report on the case of a 66-year-old woman with a right renal mass that was shown to be a clear cell carcinoma. She underwent radical nephrectomy and dendritic cell vaccination and, 3.5 years later, she developed retroperitoneal pure sarcomatous recurrence of the tumor. The authors speculate that the vaccination could have played some role in this differentiation or selection of the sarcomatous component of the primary tumor.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802006000300011&lng=en&tlng=enRenal cell carcinomaRecurrenceSarcomaNephrectomyDendritic cells
collection DOAJ
language English
format Article
sources DOAJ
author Alberto Azoubel Antunes
Marcos Francisco Dall’Oglio
José Alexandre Marzagão Barbuto
Kátia Ramos Moreira Leite
Miguel Srougi
spellingShingle Alberto Azoubel Antunes
Marcos Francisco Dall’Oglio
José Alexandre Marzagão Barbuto
Kátia Ramos Moreira Leite
Miguel Srougi
Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination
São Paulo Medical Journal
Renal cell carcinoma
Recurrence
Sarcoma
Nephrectomy
Dendritic cells
author_facet Alberto Azoubel Antunes
Marcos Francisco Dall’Oglio
José Alexandre Marzagão Barbuto
Kátia Ramos Moreira Leite
Miguel Srougi
author_sort Alberto Azoubel Antunes
title Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination
title_short Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination
title_full Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination
title_fullStr Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination
title_full_unstemmed Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination
title_sort pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination
publisher Associação Paulista de Medicina
series São Paulo Medical Journal
issn 1806-9460
description CONTEXT: Sarcomatous differentiation, which represents transformation to high-grade malignancy, can occur in all histogical types of renal malignancy. CASE REPORT: The authors report on the case of a 66-year-old woman with a right renal mass that was shown to be a clear cell carcinoma. She underwent radical nephrectomy and dendritic cell vaccination and, 3.5 years later, she developed retroperitoneal pure sarcomatous recurrence of the tumor. The authors speculate that the vaccination could have played some role in this differentiation or selection of the sarcomatous component of the primary tumor.
topic Renal cell carcinoma
Recurrence
Sarcoma
Nephrectomy
Dendritic cells
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802006000300011&lng=en&tlng=en
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