DinoSAVR struck by the TAVR asteroids
ABSTRACT Over the last decade, transcatheter aortic valve replacement (TAVR) has become the preferred treatment for patients with severe aortic stenosis at increased risk for surgery. Consequently, this new technology has been recently tested in low-risk subjects. The PARTNER 3 trial randomized 1000...
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doaj-eb5e348ad50e44408392acebe09096a12021-08-11T10:38:44ZengPermanyerREC: Interventional Cardiology (English Ed.)2604-73222019-05-011213113510.24875/RECICE.M19000036DinoSAVR struck by the TAVR asteroidsGiuseppe Tarantini0Luca Nai Fovino1Department of Cardiac, Thoracic and Vascular Sciences, University of Padua Medical School, Padua, ItalyDepartment of Cardiac, Thoracic and Vascular Sciences, University of Padua Medical School, Padua, ItalyABSTRACT Over the last decade, transcatheter aortic valve replacement (TAVR) has become the preferred treatment for patients with severe aortic stenosis at increased risk for surgery. Consequently, this new technology has been recently tested in low-risk subjects. The PARTNER 3 trial randomized 1000 patients (mean Society of Thoracic Surgeons score, 1.9%; mean age, 73 years) to undergo TAVR with a balloon-expandable valve or surgical aortic valve replacement showing that TAVR was superior in terms of the composite endpoint of death, stroke and re-hospitalization at 1 year. In the Evolut Low Risk trial that randomized 1468 patients with the use of a self-expandable prosthesis, TAVR was non-inferior to surgery for the primary composite endpoint of death or disabling stroke at 24 months. While the available 1-year follow up does not answer the question of transcatheter valves durability, these results will definitely change our everyday clinical practice.https://recintervcardiol.org/en/index.php?option=com_content&view=article&id=126Transcatheter aortic valve replacement Low surgical risk Randomized trial |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Giuseppe Tarantini Luca Nai Fovino |
spellingShingle |
Giuseppe Tarantini Luca Nai Fovino DinoSAVR struck by the TAVR asteroids REC: Interventional Cardiology (English Ed.) Transcatheter aortic valve replacement Low surgical risk Randomized trial |
author_facet |
Giuseppe Tarantini Luca Nai Fovino |
author_sort |
Giuseppe Tarantini |
title |
DinoSAVR struck by the TAVR asteroids |
title_short |
DinoSAVR struck by the TAVR asteroids |
title_full |
DinoSAVR struck by the TAVR asteroids |
title_fullStr |
DinoSAVR struck by the TAVR asteroids |
title_full_unstemmed |
DinoSAVR struck by the TAVR asteroids |
title_sort |
dinosavr struck by the tavr asteroids |
publisher |
Permanyer |
series |
REC: Interventional Cardiology (English Ed.) |
issn |
2604-7322 |
publishDate |
2019-05-01 |
description |
ABSTRACT Over the last decade, transcatheter aortic valve replacement (TAVR) has become the preferred treatment for patients with severe aortic stenosis at increased risk for surgery. Consequently, this new technology has been recently tested in low-risk subjects. The PARTNER 3 trial randomized 1000 patients (mean Society of Thoracic Surgeons score, 1.9%; mean age, 73 years) to undergo TAVR with a balloon-expandable valve or surgical aortic valve replacement showing that TAVR was superior in terms of the composite endpoint of death, stroke and re-hospitalization at 1 year. In the Evolut Low Risk trial that randomized 1468 patients with the use of a self-expandable prosthesis, TAVR was non-inferior to surgery for the primary composite endpoint of death or disabling stroke at 24 months. While the available 1-year follow up does not answer the question of transcatheter valves durability, these results will definitely change our everyday clinical practice. |
topic |
Transcatheter aortic valve replacement Low surgical risk Randomized trial |
url |
https://recintervcardiol.org/en/index.php?option=com_content&view=article&id=126 |
work_keys_str_mv |
AT giuseppetarantini dinosavrstruckbythetavrasteroids AT lucanaifovino dinosavrstruckbythetavrasteroids |
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1721211464035860480 |