Multiple choices for HIV therapy with integrase strand transfer inhibitors

<p>Abstract</p> <p>Two integrases inhibitors, raltegravir and elvitegravir, have now been approved by regulatory agencies for use in the treatment of HIV-infected patients; and the approval of a third such drug, dolutegravir, is expected during 2013 on the basis of several phase 3...

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Bibliographic Details
Main Authors: Raffi Francois, Wainberg Mark A
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Retrovirology
Subjects:
Online Access:http://www.retrovirology.com/content/9/1/110
Description
Summary:<p>Abstract</p> <p>Two integrases inhibitors, raltegravir and elvitegravir, have now been approved by regulatory agencies for use in the treatment of HIV-infected patients; and the approval of a third such drug, dolutegravir, is expected during 2013 on the basis of several phase 3 clinical trials. The advent of this new class of antiretroviral (ARV) medications represents a major advance in the management of HIV infection, and each of these three drugs can be expected to continue to be an important component of ARV combination regimens.</p>
ISSN:1742-4690