Application and practice of integrated diagnosis of glioma

• Main Authors: Hai⁃nan LI, Zhi LI
• Format: Article
• Language: English
• Published: Tianjin Huanhu Hospital 2019-12-01
• Series: Chinese Journal of Contemporary Neurology and Neurosurgery
• Subjects: glioma; pathology, molecular; integrated diagnosis (not in mesh); review
• Online Access: http://www.cjcnn.org/index.php/cjcnn/article/view/2059

Since the publication of the 2016 WHO of Tumors of the Central Nervous System (hereinafter referred to as 2016 WHO), many pathologists face challenges and confusion in "integrated diagnosis" practices of 2016 WHO due to financial or technical problems. In this review, the authors combines their practice experiences and their understanding of "cIMPACT ⁃ NOW update 1-4", and they discuss the hot issues of "integrated diagnosis", including: how to diagnose astrocytoma and oligodendroglioma, how to diagnose glioma with H3 gene mutation, How to diagnose IDH wild⁃type/H3 wild⁃type glioma and how to diagnose pediatric glioma. It is hopeful for helping Chinese neuropathologists to have a better understanding of glioma diagnostic terminology. DOI：10.3969/j.issn.1672⁃6731.2019.12.003