Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields

Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields

The heating performance of magnetic nanoparticles (MNPs) under an alternating magnetic field (AMF) is dependent on several factors. Optimizing these factors improves the heating efficiency for cancer therapy and meanwhile lowers the MNP treatment dosage. AMF is one of the most easily controllable va...

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Main Authors: Kai Wu, Jian-Ping Wang
Format: Article
Language:English
Published: AIP Publishing LLC 2017-05-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.4978458
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spelling doaj-eb8a246907454ab9877f76d6f3c9930e2020-11-25T00:27:33ZengAIP Publishing LLCAIP Advances2158-32262017-05-0175056327056327-810.1063/1.4978458342791ADVMagnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fieldsKai Wu0Jian-Ping Wang1The Center for Micromagnetics and Information Technologies (MINT) and Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USAThe Center for Micromagnetics and Information Technologies (MINT) and Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USAThe heating performance of magnetic nanoparticles (MNPs) under an alternating magnetic field (AMF) is dependent on several factors. Optimizing these factors improves the heating efficiency for cancer therapy and meanwhile lowers the MNP treatment dosage. AMF is one of the most easily controllable variables to enhance the efficiency of heat generation. This paper investigated the optimal magnetic field strength and frequency for an assembly of magnetite nanoparticles. For hyperthermia treatment in clinical applications, monodispersed NPs are forming nanoclusters in target regions where a strong magnetically interactive environment is anticipated, which leads to a completely different situation than MNPs in ferrofluids. Herein, the energy barrier model is revisited and Néel relaxation time is tailored for high MNP packing densities. AMF strength and frequency are customized for different magnetite NPs to achieve the highest power generation and the best hyperthermia performance.http://dx.doi.org/10.1063/1.4978458
collection DOAJ
language English
format Article
sources DOAJ
author Kai Wu
Jian-Ping Wang
spellingShingle Kai Wu
Jian-Ping Wang
Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields
AIP Advances
author_facet Kai Wu
Jian-Ping Wang
author_sort Kai Wu
title Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields
title_short Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields
title_full Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields
title_fullStr Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields
title_full_unstemmed Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields
title_sort magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields
publisher AIP Publishing LLC
series AIP Advances
issn 2158-3226
publishDate 2017-05-01
description The heating performance of magnetic nanoparticles (MNPs) under an alternating magnetic field (AMF) is dependent on several factors. Optimizing these factors improves the heating efficiency for cancer therapy and meanwhile lowers the MNP treatment dosage. AMF is one of the most easily controllable variables to enhance the efficiency of heat generation. This paper investigated the optimal magnetic field strength and frequency for an assembly of magnetite nanoparticles. For hyperthermia treatment in clinical applications, monodispersed NPs are forming nanoclusters in target regions where a strong magnetically interactive environment is anticipated, which leads to a completely different situation than MNPs in ferrofluids. Herein, the energy barrier model is revisited and Néel relaxation time is tailored for high MNP packing densities. AMF strength and frequency are customized for different magnetite NPs to achieve the highest power generation and the best hyperthermia performance.
url http://dx.doi.org/10.1063/1.4978458
work_keys_str_mv AT kaiwu magnetichyperthermiaperformanceofmagnetitenanoparticleassembliesunderdifferentdrivingfields
AT jianpingwang magnetichyperthermiaperformanceofmagnetitenanoparticleassembliesunderdifferentdrivingfields
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