γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection

γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection

Protective immunity against mycobacterial infections such as Mycobacterium tuberculosis is mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantial...

Full description

Bibliographic Details
Main Authors: Serena Meraviglia, Sary El Daker, Francesco Dieli, Federico Martini, Angelo Martino
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2011/587315
id doaj-eb8cf8019112490391a0c8fe7e9eac35
record_format Article
spelling doaj-eb8cf8019112490391a0c8fe7e9eac352020-11-24T21:40:57ZengHindawi LimitedClinical and Developmental Immunology1740-25221740-25302011-01-01201110.1155/2011/587315587315γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis InfectionSerena Meraviglia0Sary El Daker1Francesco Dieli2Federico Martini3Angelo Martino4Dipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Università di Palermo, 90134 Palermo, ItalyLaboratory of Cellular Immunology, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, 00149 Rome, ItalyDipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Università di Palermo, 90134 Palermo, ItalyLaboratory of Cellular Immunology, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, 00149 Rome, ItalyLaboratory of Cellular Immunology, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, 00149 Rome, ItalyProtective immunity against mycobacterial infections such as Mycobacterium tuberculosis is mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantially may influence the subsequent adaptive host response. During the early phases of infection, innate lymphocyte subsets play a pivotal role in this context. Here we summarize the findings of recent investigations on γδ T lymphocytes and their role in tuberculosis immunity.http://dx.doi.org/10.1155/2011/587315
collection DOAJ
language English
format Article
sources DOAJ
author Serena Meraviglia
Sary El Daker
Francesco Dieli
Federico Martini
Angelo Martino
spellingShingle Serena Meraviglia
Sary El Daker
Francesco Dieli
Federico Martini
Angelo Martino
γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
Clinical and Developmental Immunology
author_facet Serena Meraviglia
Sary El Daker
Francesco Dieli
Federico Martini
Angelo Martino
author_sort Serena Meraviglia
title γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
title_short γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
title_full γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
title_fullStr γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
title_full_unstemmed γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
title_sort γδ t cells cross-link innate and adaptive immunity in mycobacterium tuberculosis infection
publisher Hindawi Limited
series Clinical and Developmental Immunology
issn 1740-2522
1740-2530
publishDate 2011-01-01
description Protective immunity against mycobacterial infections such as Mycobacterium tuberculosis is mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantially may influence the subsequent adaptive host response. During the early phases of infection, innate lymphocyte subsets play a pivotal role in this context. Here we summarize the findings of recent investigations on γδ T lymphocytes and their role in tuberculosis immunity.
url http://dx.doi.org/10.1155/2011/587315
work_keys_str_mv AT serenameraviglia gdtcellscrosslinkinnateandadaptiveimmunityinmycobacteriumtuberculosisinfection
AT saryeldaker gdtcellscrosslinkinnateandadaptiveimmunityinmycobacteriumtuberculosisinfection
AT francescodieli gdtcellscrosslinkinnateandadaptiveimmunityinmycobacteriumtuberculosisinfection
AT federicomartini gdtcellscrosslinkinnateandadaptiveimmunityinmycobacteriumtuberculosisinfection
AT angelomartino gdtcellscrosslinkinnateandadaptiveimmunityinmycobacteriumtuberculosisinfection
_version_ 1725923877033345024

Similar Items