Genetic variation in DNA-repair pathways and response to radiochemotherapy in esophageal adenocarcinoma: a retrospective cohort study of the Eastern Cooperative Oncology Group

Genetic variation in DNA-repair pathways and response to radiochemotherapy in esophageal adenocarcinoma: a retrospective cohort study of the Eastern Cooperative Oncology Group

<p>Abstract</p> <p>Background</p> <p>Recent data in esophageal cancer suggests the variant allele of a single-nucleotide polymorphism (SNP) in <it>XRCC1 </it>may be associated with resistance to radiochemotherapy. However, this SNP has not been assessed in a...

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Main Authors: Wu Xifeng, Meltzer Stephen J, Liu Geoffrey, Offer Steven M, Hafez Michael J, Montgomery Elizabeth A, Powell Mark, Philips Santosh, Skaar Todd C, Murphy Kathleen M, Catalano Paul J, Yoon Harry H, Forastiere Arlene A, Benson Al B, Kleinberg Lawrence R, Gibson Michael K
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/176

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