The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort.

Recent genome-wide association studies (GWAS) have identified several novel single nucleotide polymorphisms (SNPs) associated with type 2 diabetes (T2D). Various models using clinical and/or genetic risk factors have been developed for T2D risk prediction. However, analysis considering algorithms fo...

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Bibliographic Details
Main Authors: Daichi Shigemizu, Testuo Abe, Takashi Morizono, Todd A Johnson, Keith A Boroevich, Yoichiro Hirakawa, Toshiharu Ninomiya, Yutaka Kiyohara, Michiaki Kubo, Yusuke Nakamura, Shiro Maeda, Tatsuhiko Tsunoda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3961382?pdf=render

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