Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.
BACKGROUND:The lack of a suitable animal model to study viral and immunological mechanisms of human dengue disease has been a deterrent to dengue research. METHODOLOGY/PRINCIPAL FINDINGS:We sought to establish an animal model for dengue virus (DENV) infection and immunity using non-obese diabetic/se...
Main Authors: | Smita Jaiswal, Todd Pearson, Heather Friberg, Leonard D Shultz, Dale L Greiner, Alan L Rothman, Anuja Mathew |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-10-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2749937?pdf=render |
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