Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune responseResearch in Context
Background: Sphingomyelin synthase 1 (SMS1) has been reported to participate in hepatitis and atherosclerosis. However, its role in autoimmune response is not clear. This study investigates the possible involvement of SMS1 in B-cell activation and lupus-like autoimmunity. Methods: SMS1 knockout lupu...
Main Authors: | Chenqiong Wang, Bingxia Ming, Xuefen Wu, Tong Wu, Shaozhe Cai, Peng Hu, Jungen Tang, Zheng Tan, Chaohong Liu, Jixin Zhong, Fang Zheng, Lingli Dong |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | EBioMedicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396419304190 |
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