Immunophysical Evaluation of the Initiating Step in the Formation of the Membrane Attack Complex

The complex between complement system proteins C5b and C6 is the cornerstone for the assembly of the membrane attack complex (MAC, also known as C5b6789n). MAC is the terminal product of three converging pathways of the complement system and functions as a pore forming complex on cell surfaces, as a...

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Bibliographic Details
Main Authors: Nehemiah Zewde, Rohith R. Mohan, Dimitrios Morikis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphy.2018.00130/full