Fly model causes neurological rethink

A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach.

Bibliographic Details
Main Authors:	Madhumala K Sadanandappa, Mani Ramaswami
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2013-12-01
Series:	eLife
Subjects:	endosome neuropathy genetic synapse animal models of disease
Online Access:	https://elifesciences.org/articles/01820

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spelling	doaj-ec4f6dc499d4471e8b55b143ce4ecbda2021-05-04T22:51:18ZengeLife Sciences Publications LtdeLife2050-084X2013-12-01210.7554/eLife.01820Fly model causes neurological rethinkMadhumala K Sadanandappa0Mani Ramaswami1National Centre for Biological Sciences-TIFR, Bangalore, IndiaSchool of Genetics and Microbiology, School of Natural Sciences, Smurfit Institute of Genetics and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, IrelandA Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach.https://elifesciences.org/articles/01820endosomeneuropathygeneticsynapseanimal models of disease
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Madhumala K Sadanandappa Mani Ramaswami
spellingShingle	Madhumala K Sadanandappa Mani Ramaswami Fly model causes neurological rethink eLife endosome neuropathy genetic synapse animal models of disease
author_facet	Madhumala K Sadanandappa Mani Ramaswami
author_sort	Madhumala K Sadanandappa
title	Fly model causes neurological rethink
title_short	Fly model causes neurological rethink
title_full	Fly model causes neurological rethink
title_fullStr	Fly model causes neurological rethink
title_full_unstemmed	Fly model causes neurological rethink
title_sort	fly model causes neurological rethink
publisher	eLife Sciences Publications Ltd
series	eLife
issn	2050-084X
publishDate	2013-12-01
description	A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach.
topic	endosome neuropathy genetic synapse animal models of disease
url	https://elifesciences.org/articles/01820
work_keys_str_mv	AT madhumalaksadanandappa flymodelcausesneurologicalrethink AT maniramaswami flymodelcausesneurologicalrethink
_version_	1721477270203269120

Fly model causes neurological rethink

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