Long Non-Coding RNA-MALAT1 Mediates Retinal Ganglion Cell Apoptosis Through the PI3K/Akt Signaling Pathway in Rats with Glaucoma
Background/Aims: The aim of the present study is to investigate the effect of long non-coding RNA-MALAT1 (LncRNA-MALAT1) on retinal ganglion cell (RGC) apoptosis mediated by the PI3K/Akt signaling pathway in rats with glaucoma. Methods: RGCs were isolated and cultured, and monoclonal antibodies (ant...
Main Authors: | Hai-Bo Li, Qi-Sheng You, Li-Xin Xu, Li-Xin Sun, Aman Shah Abdul Majid, Xiao-Bo Xia, Dan Ji |
---|---|
Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2017-10-01
|
Series: | Cellular Physiology and Biochemistry |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/484231 |
Similar Items
-
Quercetin Declines Apoptosis, Ameliorates Mitochondrial Function and Improves Retinal Ganglion Cell Survival and Function in In Vivo Model of Glaucoma in Rat and Retinal Ganglion Cell Culture In Vitro
by: Feng-Juan Gao, et al.
Published: (2017-09-01) -
Research progress on protecting effect of taurine on retinal ganglion cells
by: Zong-Li Hu, et al.
Published: (2014-03-01) -
β-Ⅲ-Tubulin:a reliable marker for retinal ganglion cell labeling in experimental models of glaucoma
by: Shan-Ming Jiang, et al.
Published: (2015-08-01) -
Ligustrazine induces viability, suppresses apoptosis and autophagy of retinal ganglion cells with ischemia/reperfusion injury through the PI3K/Akt/mTOR signaling pathway
by: Hong-yan Du, et al.
Published: (2021-01-01) -
Risk Factors for Retinal Ganglion Cell Distress in Glaucoma and Neuroprotective Potential Intervention
by: Stefania Vernazza, et al.
Published: (2021-07-01)