Characterization of Donor Variability for γδ T Cell ex vivo Expansion and Development of an Allogeneic γδ T Cell Immunotherapy

Characterization of Donor Variability for γδ T Cell ex vivo Expansion and Development of an Allogeneic γδ T Cell Immunotherapy

Gamma delta (γδ) T cells recently emerged as an attractive candidate for cancer immunotherapy treatments due to their inherent cytotoxicity against both hematological and solid tumors. Moreover, γδ T cells provide a platform for the development of allogeneic cell therapies, as they can recognize ant...

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Bibliographic Details
Main Authors: Rebecca E. Burnham, Jaquelyn T. Zoine, Jamie Y. Story, Swetha N. Garimalla, Greg Gibson, Aaron Rae, Erich Williams, Lisa Bixby, David Archer, Christopher B. Doering, H. Trent Spencer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Medicine
Subjects:
gamma delta (γδ) T cells
allogeneic cell products
ex vivo expanded T cells
serum free expansion
mixed cell product
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.588453/full

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https://www.frontiersin.org/articles/10.3389/fmed.2020.588453/full

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