PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation

PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation

PHF20 is a core component of the lysine acetyltransferase complex MOF (male absent on the first)-NSL (non-specific lethal) that generates the major epigenetic mark H4K16ac and is necessary for transcriptional regulation and DNA repair. The role of PHF20 in the complex remains elusive. Here, we repor...

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Bibliographic Details
Main Authors: Brianna J. Klein, Xiaoyan Wang, Gaofeng Cui, Chao Yuan, Maria Victoria Botuyan, Kevin Lin, Yue Lu, Xiaolu Wang, Yue Zhao, Christiane J. Bruns, Georges Mer, Xiaobing Shi, Tatiana G. Kutateladze
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Cell Reports
Subjects:
PHF20
MOF
p53
histone methylation
histone acetylation
PHD finger
Tudor
chromatin
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716312955

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