Analytical Enantio-Separation of Linagliptin in Linagliptin and Metformin HCl Dosage Forms by Applying Two-Level Factorial Design
A novel, stability indicating, reverse phase high-performance liquid chromatography (RP-HPLC) method was developed to determine the S-isomer of linagliptin (LGP) in linagliptin and metformin hydrochloride (MET HCl) tablets (LGP–MET HCl) by implementing design of experiment (DoE), i.e., two-level, fu...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Österreichische Apotheker-Verlagsgesellschaft m. b. H.
2016-10-01
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| Series: | Scientia Pharmaceutica |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2218-0532/84/4/671 |