A quantitative model for the rate-limiting process of UGA alternative assignments to stop and selenocysteine codons.

A quantitative model for the rate-limiting process of UGA alternative assignments to stop and selenocysteine codons.

Ambiguity in genetic codes exists in cases where certain stop codons are alternatively used to encode non-canonical amino acids. In selenoprotein transcripts, the UGA codon may either represent a translation termination signal or a selenocysteine (Sec) codon. Translating UGA to Sec requires selenium...

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Bibliographic Details
Main Authors: Yen-Fu Chen, Hsiu-Chuan Lin, Kai-Neng Chuang, Chih-Hsu Lin, Hsueh-Chi S Yen, Chen-Hsiang Yeang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5323020?pdf=render

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