Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil.
Public hospital emergency room (ER) in Porto Alegre, Brazil, a setting with high prevalence of tuberculosis (TB) and human immunodeficiency virus (HIV) infection.To determine the prevalence of PTB, using a symptom based active case finding (ACF) strategy in the ER of a public hospital in an area wit...
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doaj-ec8908cc8b8f4a428c8ec9761fde83b72020-11-24T21:38:57ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0199e10757610.1371/journal.pone.0107576Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil.Denise Rossato SilvaAlice Mânica MüllerKarina da Silva TomasiniPaulo de Tarso Roth DalcinJonathan E GolubMarcus Barreto CondePublic hospital emergency room (ER) in Porto Alegre, Brazil, a setting with high prevalence of tuberculosis (TB) and human immunodeficiency virus (HIV) infection.To determine the prevalence of PTB, using a symptom based active case finding (ACF) strategy in the ER of a public hospital in an area with high prevalence of TB and HIV, as well as variables associated with pulmonary TB diagnosis.Cross sectional study. All patients ≥ 18 years seeking care at the ER were screened for respiratory symptoms and those with cough ≥ 2 weeks were invited to provide a chest radiograph and two unsupervised samples of sputum for acid-fast bacilli smear and culture.Among 31,267 admissions, 6,273 (20.1%) reported respiratory symptoms; 197 reported cough ≥ 2 weeks, of which pulmonary TB was diagnosed in 30. In multivariate analysis, the variables associated with a pulmonary tuberculosis diagnosis were: age (OR 0.94, 95% CI: 0.92-0.97; p<0.0001), sputum production (OR 0.18, 95% CI 0.06-0.56; p = 0.003), and radiographic findings typical of TB (OR 12.11, 95% CI 4.45-32.93; p<0.0001).This study identified a high prevalence of pulmonary TB among patients who sought care at the emergency department of a tertiary hospital, emphasizing the importance of regular screening of all comers for active TB in this setting.http://europepmc.org/articles/PMC4161448?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Denise Rossato Silva Alice Mânica Müller Karina da Silva Tomasini Paulo de Tarso Roth Dalcin Jonathan E Golub Marcus Barreto Conde |
spellingShingle |
Denise Rossato Silva Alice Mânica Müller Karina da Silva Tomasini Paulo de Tarso Roth Dalcin Jonathan E Golub Marcus Barreto Conde Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. PLoS ONE |
author_facet |
Denise Rossato Silva Alice Mânica Müller Karina da Silva Tomasini Paulo de Tarso Roth Dalcin Jonathan E Golub Marcus Barreto Conde |
author_sort |
Denise Rossato Silva |
title |
Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. |
title_short |
Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. |
title_full |
Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. |
title_fullStr |
Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. |
title_full_unstemmed |
Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. |
title_sort |
active case finding of tuberculosis (tb) in an emergency room in a region with high prevalence of tb in brazil. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2014-01-01 |
description |
Public hospital emergency room (ER) in Porto Alegre, Brazil, a setting with high prevalence of tuberculosis (TB) and human immunodeficiency virus (HIV) infection.To determine the prevalence of PTB, using a symptom based active case finding (ACF) strategy in the ER of a public hospital in an area with high prevalence of TB and HIV, as well as variables associated with pulmonary TB diagnosis.Cross sectional study. All patients ≥ 18 years seeking care at the ER were screened for respiratory symptoms and those with cough ≥ 2 weeks were invited to provide a chest radiograph and two unsupervised samples of sputum for acid-fast bacilli smear and culture.Among 31,267 admissions, 6,273 (20.1%) reported respiratory symptoms; 197 reported cough ≥ 2 weeks, of which pulmonary TB was diagnosed in 30. In multivariate analysis, the variables associated with a pulmonary tuberculosis diagnosis were: age (OR 0.94, 95% CI: 0.92-0.97; p<0.0001), sputum production (OR 0.18, 95% CI 0.06-0.56; p = 0.003), and radiographic findings typical of TB (OR 12.11, 95% CI 4.45-32.93; p<0.0001).This study identified a high prevalence of pulmonary TB among patients who sought care at the emergency department of a tertiary hospital, emphasizing the importance of regular screening of all comers for active TB in this setting. |
url |
http://europepmc.org/articles/PMC4161448?pdf=render |
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