Unconventional Secretion and Intercellular Transfer of Mutant Huntingtin
The mechanism of intercellular transmission of pathological agents in neurodegenerative diseases has received much recent attention. Huntington’s disease (HD) is caused by a monogenic mutation in the gene encoding Huntingtin (HTT). Mutant HTT (mHTT) harbors a CAG repeat extension which enc...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-06-01
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| Series: | Cells |
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| Online Access: | http://www.mdpi.com/2073-4409/7/6/59 |