Measurement of Adenosine Deaminase in Ascitic Fluid Contributed to the Diagnosis in a Case of Tuberculous Peritonitis

A diagnosis of tuberculous peritonitis (TBP) is difficult because of nonspecific manifestation and limited effectiveness of conventional diagnostic tools. Recently, the usability of measurement of ascitic adenosine deaminase (ADA) was shown. We report here a case of TBP in which measurement of ascit...

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Main Authors: Kenichi Kishimoto, Tsuyoshi Mishiro, Hironobu Mikami, Noritsugu Yamashita, Kazushi Hara, Wataru Hamamoto, Yuumi Cho, Yukihiro Ikuta, Makoto Nagasaki, Yoshikazu Kinoshita
Format: Article
Language:English
Published: Karger Publishers 2019-07-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:https://www.karger.com/Article/FullText/501066
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spelling doaj-eca271ab14734e48a80ca28db297d58d2020-11-25T01:29:36ZengKarger PublishersCase Reports in Gastroenterology1662-06312019-07-0113229930410.1159/000501066501066Measurement of Adenosine Deaminase in Ascitic Fluid Contributed to the Diagnosis in a Case of Tuberculous PeritonitisKenichi KishimotoTsuyoshi MishiroHironobu MikamiNoritsugu YamashitaKazushi HaraWataru HamamotoYuumi ChoYukihiro IkutaMakoto NagasakiYoshikazu KinoshitaA diagnosis of tuberculous peritonitis (TBP) is difficult because of nonspecific manifestation and limited effectiveness of conventional diagnostic tools. Recently, the usability of measurement of ascitic adenosine deaminase (ADA) was shown. We report here a case of TBP in which measurement of ascitic ADA contributed to the diagnosis. A 93-year-old male developed a large amount of ascites. Analyses of the ascitic fluid revealed exudation, though antibiotics treatment was ineffective. Using paracentesis, the ADA level in the ascites was measured and shown to be high. Under suspicion of TBP, an exploratory laparoscopy was performed and a definitive diagnosis of TBP was made.https://www.karger.com/Article/FullText/501066Tuberculous peritonitisAscitesAdenosine deaminase
collection DOAJ
language English
format Article
sources DOAJ
author Kenichi Kishimoto
Tsuyoshi Mishiro
Hironobu Mikami
Noritsugu Yamashita
Kazushi Hara
Wataru Hamamoto
Yuumi Cho
Yukihiro Ikuta
Makoto Nagasaki
Yoshikazu Kinoshita
spellingShingle Kenichi Kishimoto
Tsuyoshi Mishiro
Hironobu Mikami
Noritsugu Yamashita
Kazushi Hara
Wataru Hamamoto
Yuumi Cho
Yukihiro Ikuta
Makoto Nagasaki
Yoshikazu Kinoshita
Measurement of Adenosine Deaminase in Ascitic Fluid Contributed to the Diagnosis in a Case of Tuberculous Peritonitis
Case Reports in Gastroenterology
Tuberculous peritonitis
Ascites
Adenosine deaminase
author_facet Kenichi Kishimoto
Tsuyoshi Mishiro
Hironobu Mikami
Noritsugu Yamashita
Kazushi Hara
Wataru Hamamoto
Yuumi Cho
Yukihiro Ikuta
Makoto Nagasaki
Yoshikazu Kinoshita
author_sort Kenichi Kishimoto
title Measurement of Adenosine Deaminase in Ascitic Fluid Contributed to the Diagnosis in a Case of Tuberculous Peritonitis
title_short Measurement of Adenosine Deaminase in Ascitic Fluid Contributed to the Diagnosis in a Case of Tuberculous Peritonitis
title_full Measurement of Adenosine Deaminase in Ascitic Fluid Contributed to the Diagnosis in a Case of Tuberculous Peritonitis
title_fullStr Measurement of Adenosine Deaminase in Ascitic Fluid Contributed to the Diagnosis in a Case of Tuberculous Peritonitis
title_full_unstemmed Measurement of Adenosine Deaminase in Ascitic Fluid Contributed to the Diagnosis in a Case of Tuberculous Peritonitis
title_sort measurement of adenosine deaminase in ascitic fluid contributed to the diagnosis in a case of tuberculous peritonitis
publisher Karger Publishers
series Case Reports in Gastroenterology
issn 1662-0631
publishDate 2019-07-01
description A diagnosis of tuberculous peritonitis (TBP) is difficult because of nonspecific manifestation and limited effectiveness of conventional diagnostic tools. Recently, the usability of measurement of ascitic adenosine deaminase (ADA) was shown. We report here a case of TBP in which measurement of ascitic ADA contributed to the diagnosis. A 93-year-old male developed a large amount of ascites. Analyses of the ascitic fluid revealed exudation, though antibiotics treatment was ineffective. Using paracentesis, the ADA level in the ascites was measured and shown to be high. Under suspicion of TBP, an exploratory laparoscopy was performed and a definitive diagnosis of TBP was made.
topic Tuberculous peritonitis
Ascites
Adenosine deaminase
url https://www.karger.com/Article/FullText/501066
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