A vault nanoparticle vaccine induces protective mucosal immunity.

A vault nanoparticle vaccine induces protective mucosal immunity.

Generation of robust cell-mediated immune responses at mucosal surfaces while reducing overall inflammation is a primary goal for vaccination. Here we report the use of a recombinant nanoparticle as a vaccine delivery platform against mucosal infections requiring T cell-mediated immunity for eradica...

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Bibliographic Details
Main Authors: Cheryl I Champion, Valerie A Kickhoefer, Guangchao Liu, Raymond J Moniz, Amanda S Freed, Liisa L Bergmann, Dana Vaccari, Sujna Raval-Fernandes, Ann M Chan, Leonard H Rome, Kathleen A Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2671841?pdf=render

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