Quantification of Cell-free HER-2 DNA in Plasma from Breast Cancer Patients: Sensitivity for Detection of Metastatic Recurrence and Gene Amplification

Quantification of Cell-free HER-2 DNA in Plasma from Breast Cancer Patients: Sensitivity for Detection of Metastatic Recurrence and Gene Amplification

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The purpose of this study was to quantify the free-circu‐ lating plasma HER-2 DNA (cfHER-2 DNA) and to assess the ability of analysis to discriminate between patients with primary breast cancer and healthy controls in order to detect metastatic recurrence in comparison with serum HER-2 protein and a...

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Bibliographic Details
Main Authors: Patricia Diana Sørensen, Rikke Fredslund Andersen, Niels Pallisgaard, Jonna Skov Madsen, Erik Hugger Jakobsen, Ivan Brandslund
Format: Article
Language:English
Published: AboutScience Srl 2015-08-01
Series:Journal of Circulating Biomarkers
Subjects:
breast cancer
cell-free DNA
gene amplifica‐ tion
HER-2
metastatic recurrence
sensitivity
Online Access:http://www.intechopen.com/journals/journal-of-circulating-biomarkers/quantification-of-cell-free-her-2-dna-in-plasma-from-breast-cancer-patients-sensitivity-for-detectio

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