Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications

Automation in combination with high throughput screening methods has revolutionised molecular biology in the last two decades. Today, many combinatorial libraries as well as several systems for automation are available. Depending on scope, budget and time, a different combination of library and expe...

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Bibliographic Details
Main Authors: Jörn Glökler, Tatjana Schütze, Zoltán Konthur
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/4/2478/
Description
Summary:Automation in combination with high throughput screening methods has revolutionised molecular biology in the last two decades. Today, many combinatorial libraries as well as several systems for automation are available. Depending on scope, budget and time, a different combination of library and experimental handling might be most effective. In this review we will discuss several concepts of combinatorial libraries and provide information as what to expect from these depending on the given context.
ISSN:1420-3049