Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications

Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications

Automation in combination with high throughput screening methods has revolutionised molecular biology in the last two decades. Today, many combinatorial libraries as well as several systems for automation are available. Depending on scope, budget and time, a different combination of library and expe...

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Bibliographic Details
Main Authors: Jörn Glökler, Tatjana Schütze, Zoltán Konthur
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:Molecules
Subjects:
phage display
SELEX
automation
random combinatorial library
in vitro evolution
Online Access:http://www.mdpi.com/1420-3049/15/4/2478/
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spelling doaj-ecbe297fd1234c8d99111d5642093acb2020-11-24T23:13:04ZengMDPI AGMolecules1420-30492010-04-011542478249010.3390/molecules15042478Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select ApplicationsJörn GlöklerTatjana SchützeZoltán KonthurAutomation in combination with high throughput screening methods has revolutionised molecular biology in the last two decades. Today, many combinatorial libraries as well as several systems for automation are available. Depending on scope, budget and time, a different combination of library and experimental handling might be most effective. In this review we will discuss several concepts of combinatorial libraries and provide information as what to expect from these depending on the given context. http://www.mdpi.com/1420-3049/15/4/2478/phage displaySELEXautomationrandom combinatorial libraryin vitro evolution
collection DOAJ
language English
format Article
sources DOAJ
author Jörn Glökler
Tatjana Schütze
Zoltán Konthur
spellingShingle Jörn Glökler
Tatjana Schütze
Zoltán Konthur
Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications
Molecules
phage display
SELEX
automation
random combinatorial library
in vitro evolution
author_facet Jörn Glökler
Tatjana Schütze
Zoltán Konthur
author_sort Jörn Glökler
title Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications
title_short Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications
title_full Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications
title_fullStr Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications
title_full_unstemmed Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications
title_sort automation in the high-throughput selection of random combinatorial libraries—different approaches for select applications
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2010-04-01
description Automation in combination with high throughput screening methods has revolutionised molecular biology in the last two decades. Today, many combinatorial libraries as well as several systems for automation are available. Depending on scope, budget and time, a different combination of library and experimental handling might be most effective. In this review we will discuss several concepts of combinatorial libraries and provide information as what to expect from these depending on the given context.
topic phage display
SELEX
automation
random combinatorial library
in vitro evolution
url http://www.mdpi.com/1420-3049/15/4/2478/
work_keys_str_mv AT jornglokler automationinthehighthroughputselectionofrandomcombinatoriallibrariesdifferentapproachesforselectapplications
AT tatjanaschutze automationinthehighthroughputselectionofrandomcombinatoriallibrariesdifferentapproachesforselectapplications
AT zoltankonthur automationinthehighthroughputselectionofrandomcombinatoriallibrariesdifferentapproachesforselectapplications
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