TNFα inhibitor may be effective for severe COVID-19: learning from toxic epidermal necrolysis
Increased inflammatory cytokines [such as tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6)] are observed in COVID-19 patients, especially in the severe group. The phenomenon of a cytokine storm may be the central inducer of apoptosis of alveolar epithelial cells, which leads to rapid prog...
Main Authors: | Xue-Yan Chen, Bing-Xi Yan, Xiao-Yong Man |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-05-01
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Series: | Therapeutic Advances in Respiratory Disease |
Online Access: | https://doi.org/10.1177/1753466620926800 |
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