Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb
The potential toxic effects of mancozeb exposure on some antioxidant enzyme were investigated on heart tissue of zebrafish in this study. Zebrafish groups were exposed to different doses of mancozeb (Group A: 5 mgL-1 and Group B: 7.5 mgL-1) for 120 hours. In this study, catalase (CAT) activity, malo...
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Ege University
2019-12-01
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doaj-ed037bc223724d9ca9bbf9d156a7d8d02021-04-01T09:32:44ZengEge UniversitySu Ürünleri Dergisi2148-31402019-12-0136432532810.12714/egejfas.36.4.0252Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozebŞeyma Kızılkaya0Harika Eylül Esmer Duruel1Figen Esin Kayhan2Güllü Kaymak3MARMARA ÜNİVERSİTESİMARMARA ÜNİVERSİTESİMARMARA ÜNİVERSİTESİMARMARA ÜNİVERSİTESİThe potential toxic effects of mancozeb exposure on some antioxidant enzyme were investigated on heart tissue of zebrafish in this study. Zebrafish groups were exposed to different doses of mancozeb (Group A: 5 mgL-1 and Group B: 7.5 mgL-1) for 120 hours. In this study, catalase (CAT) activity, malondialdehyde (MDA) level and total protein (TP) level were determined with spectrophotometer. Our results showed that CAT activity was found 2,541±0,771 mg L-1 in A group and 2,011±0,201 mg L-1 in B group in this study. CAT and MDA activity levels decreased in the experiment group according to control group. MDA levels were found 0,025±0,003 mg L-1 in A group and 0,025±0,003 mg L-1 in B group. TP levels were found 9,75±1,51 mg L-1 in A group and 10,18±0,32 mg L-1 in B group. TP levels increased in the all experiment groups according to control group. We observed that the changes in the CAT activity and MDA levels were time and as well as mancozeb dose dependent. As a result mancozeb is a very toxic substance for zebrafish and other aquatic organisms.https://dergipark.org.tr/tr/pub/egejfas/issue/46718/522711mancozeboxidative stresscatalasemalondialdehydezebrafishmancozeboksidatif streskatalazmalondialdehitzebra balığı |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Şeyma Kızılkaya Harika Eylül Esmer Duruel Figen Esin Kayhan Güllü Kaymak |
spellingShingle |
Şeyma Kızılkaya Harika Eylül Esmer Duruel Figen Esin Kayhan Güllü Kaymak Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb Su Ürünleri Dergisi mancozeb oxidative stress catalase malondialdehyde zebrafish mancozeb oksidatif stres katalaz malondialdehit zebra balığı |
author_facet |
Şeyma Kızılkaya Harika Eylül Esmer Duruel Figen Esin Kayhan Güllü Kaymak |
author_sort |
Şeyma Kızılkaya |
title |
Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb |
title_short |
Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb |
title_full |
Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb |
title_fullStr |
Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb |
title_full_unstemmed |
Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb |
title_sort |
some oxidative stress parameters in heart tissue of zebrafish (danio reiro) caused by mancozeb |
publisher |
Ege University |
series |
Su Ürünleri Dergisi |
issn |
2148-3140 |
publishDate |
2019-12-01 |
description |
The potential toxic effects of mancozeb exposure on some antioxidant enzyme were investigated on heart tissue of zebrafish in this study. Zebrafish groups were exposed to different doses of mancozeb (Group A: 5 mgL-1 and Group B: 7.5 mgL-1) for 120 hours. In this study, catalase (CAT) activity, malondialdehyde (MDA) level and total protein (TP) level were determined with spectrophotometer. Our results showed that CAT activity was found 2,541±0,771 mg L-1 in A group and 2,011±0,201 mg L-1 in B group in this study. CAT and MDA activity levels decreased in the experiment group according to control group. MDA levels were found 0,025±0,003 mg L-1 in A group and 0,025±0,003 mg L-1 in B group. TP levels were found 9,75±1,51 mg L-1 in A group and 10,18±0,32 mg L-1 in B group. TP levels increased in the all experiment groups according to control group. We observed that the changes in the CAT activity and MDA levels were time and as well as mancozeb dose dependent. As a result mancozeb is a very toxic substance for zebrafish and other aquatic organisms. |
topic |
mancozeb oxidative stress catalase malondialdehyde zebrafish mancozeb oksidatif stres katalaz malondialdehit zebra balığı |
url |
https://dergipark.org.tr/tr/pub/egejfas/issue/46718/522711 |
work_keys_str_mv |
AT seymakızılkaya someoxidativestressparametersinhearttissueofzebrafishdanioreirocausedbymancozeb AT harikaeylulesmerduruel someoxidativestressparametersinhearttissueofzebrafishdanioreirocausedbymancozeb AT figenesinkayhan someoxidativestressparametersinhearttissueofzebrafishdanioreirocausedbymancozeb AT gullukaymak someoxidativestressparametersinhearttissueofzebrafishdanioreirocausedbymancozeb |
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