Analysis of the relations between allergen specific LgG antibody and allergic dermatosis of 14 kinds foods

• Main Authors: Yin’e Hu, Shufang Dai, Bin Wang, Wei Qu, Junling Gao, Aqeel Ashraf Muhammad
• Format: Article
• Language: English
• Published: De Gruyter 2015-01-01
• Series: Open Medicine
• Subjects: food-specific IgG antibody; allergy dermatoses; food intolerance
• Online Access: http://www.degruyter.com/view/j/med.2015.10.issue-1/med-2015-0070/med-2015-0070.xml?format=INT

To use food-specific IgG antibody detection to explore its application in the allergy dermatoses. 181 patients were included from January 2014 to September 2014. Fourteen food-specific IgG antibodies were detected by ELISA. The positive rates of IgG antibody of the patient group and the healthy group were significantly different. The positive rates of IgG antibody of egg, milk, shrimp and crab took a large proportion in three groups of patients with three kinds of allergy dermatoses of urticaria, eczema and allergic dermatitis, the proportion of which was respectively 70.2%, 77.8% and 71.7%. There was mild and moderate intolerance of food in the allergic dermatitis group while there was no distribution difference of food intolerance in urticaria group and eczema group. Among urticaria and allergic dermatitis patients with positive antibody, the positive rate of children was significantly higher than that of adults while there was no significant difference between children and adults among eczema patients with positive antibody. Allergy dermatoses are closely related to food-specific IgG antibody and the allergy dermatoses patients have a high incidence rate of food intolerance; detecting IgG antibody in patients is of great significance for the diagnosis and treatment of allergy dermatoses.