Botulinum Toxin Type A Induces Changes in the Chemical Coding of Substance P-Immunoreactive Dorsal Root Ganglia Sensory Neurons Supplying the Porcine Urinary Bladder

Botulinum Toxin Type A Induces Changes in the Chemical Coding of Substance P-Immunoreactive Dorsal Root Ganglia Sensory Neurons Supplying the Porcine Urinary Bladder

Botulinum toxin (BTX) is a potent neurotoxin which blocks acetylcholine release from nerve terminals, and therefore leads to cessation of somatic motor and/or parasympathetic transmission. Recently it has been found that BTX also interferes with sensory transmission, thus, the present study was aime...

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Bibliographic Details
Main Authors: Agnieszka Bossowska, Ewa Lepiarczyk, Urszula Mazur, Paweł Janikiewicz, Włodzimierz Markiewicz
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Toxins
Subjects:
botulinum toxin A
urinary bladder
sensory innervation
dorsal root ganglia
substance P
neurotransmitters
pain
immunohistochemistry
pig
Online Access:http://www.mdpi.com/2072-6651/7/11/4797

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