Pediatric Patients With Steroid-Sensitive Nephrotic Syndrome Have Higher Expression of T Regulatory Lymphocytes in Comparison to Steroid-Resistant Disease

Pediatric Patients With Steroid-Sensitive Nephrotic Syndrome Have Higher Expression of T Regulatory Lymphocytes in Comparison to Steroid-Resistant Disease

Background and Aim: Idiopathic nephrotic syndrome (INS) is classified according to the response to drug therapy in steroid-sensitive (SS), steroid-dependent (SD), and steroid-resistant (SR) categories. Previous studies showed changes in inflammatory activity of subpopulations of lymphocytes in INS....

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Main Authors: Fabio Tadeu Lourenço Guimarães, Rodrigo Novaes Ferreira, Gustavo Eustáquio Alvim Brito-Melo, Etel Rocha-Vieira, Wagner de Fátima Pereira, Sérgio Veloso Brant Pinheiro, Aline Silva Miranda, Ana Cristina Simões e Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pediatrics
Subjects:
nephrotic syndrome
flow cytometry
regulatory T cells
integrins
chemokines
Online Access:https://www.frontiersin.org/article/10.3389/fped.2019.00114/full

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