Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations

Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations

CRISPR-Cas provides a barrier to horizontal gene transfer in prokaryotes. It was previously observed that functional CRISPR-Cas systems are absent from multidrug-resistant (MDR) Enterococcus faecalis, which only possess an orphan CRISPR locus, termed CRISPR2, lacking cas genes. Here, we investigate...

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Bibliographic Details
Main Authors: Karthik Hullahalli, Marinelle Rodrigues, Kelli L Palmer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
Enterococcus faecalis
plasmid
CRISPR
antibiotic resistance
Online Access:https://elifesciences.org/articles/26664

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