Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties.

BACKGROUND: Several beneficial effects have been demonstrated for secretogranin II (SgII) in non-cardiac tissue. As cardiac production of chromogranin A and B, two related proteins, is increased in heart failure (HF), we hypothesized that SgII could play a role in cardiovascular pathophysiology. MET...

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Main Authors: Helge Røsjø, Mats Stridsberg, Geir Florholmen, Kåre-Olav Stensløkken, Anett Hellebø Ottesen, Ivar Sjaastad, Cathrine Husberg, Mai Britt Dahl, Erik Øie, William E Louch, Torbjørn Omland, Geir Christensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3360055?pdf=render