Histopathological and molecular diagnosis of Mycoplasma sp. infection in rats kept in a conventional animal facility </br> Diagnóstico histopatológico e molecular da infecção por Mycoplasma sp. em ratos mantidos em biotério convencional

The chronic infection by Mycoplasma pulmonis is frequently found in rats kept in conventional premises and may influence the results of the experiments conducted using these animals. During the clinical presentation of the infection animals develop among other manifestations clinical signs of resp...

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Bibliographic Details
Main Authors: Sandra Fernandez, Jane Silveira Fraga, Ronei Saldanha Lopes, Rosangela Boeck, Fernando Rosado Spilki
Format: Article
Language:English
Published: Universidade Estadual de Londrina 2010-12-01
Series:Semina: Ciências Agrárias
Subjects:
Online Access:http://www.uel.br/revistas/uel/index.php/semagrarias/article/view/2017
Description
Summary:The chronic infection by Mycoplasma pulmonis is frequently found in rats kept in conventional premises and may influence the results of the experiments conducted using these animals. During the clinical presentation of the infection animals develop among other manifestations clinical signs of respiratory system impairment. On the present study, we report the diagnosis the histopathological and molecular diagnosis of Mycoplasma sp. infection in Wistar rats both presenting clinical signs of infection and health animals kept in the same colony. The efficacy of therapeutic and prophylactic actions is discussed.<p><p>A infecção crônica por Mycoplasma pulmonis é freqüentemente encontrada em ratos alojados em biotérios convencionais e pode influir no resultado dos experimentos realizados com tais animais. Na forma clínica da infecção os animais desenvolvem dentre outras manifestações sinais de comprometimento do sistema respiratório. No presente estudo, relatamos o diagnóstico histopatológico e molecular da infecção por Mycoplasma sp., tanto em ratos Wistar apresentando sinais da infecção quanto em animais saudáveis mantidos na mesma colônia. A eficácia de medidas terapêuticas e profiláticas é discutida.
ISSN:1676-546X
1679-0359