Potentiality of multiple modalities for single-cell analyses to evaluate the tumor microenvironment in clinical specimens

Potentiality of multiple modalities for single-cell analyses to evaluate the tumor microenvironment in clinical specimens

Abstract Single-cell level analysis is powerful tool to assess the heterogeneity of cellular components in tumor microenvironments (TME). In this study, we investigated immune-profiles using the single-cell analyses of endoscopically- or surgically-resected tumors, and peripheral blood mononuclear c...

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Main Authors: Yukie Kashima, Yosuke Togashi, Shota Fukuoka, Takahiro Kamada, Takuma Irie, Ayako Suzuki, Yoshiaki Nakamura, Kohei Shitara, Tatsunori Minamide, Taku Yoshida, Naofumi Taoka, Tatsuya Kawase, Teiji Wada, Koichiro Inaki, Masataka Chihara, Yukihiko Ebisuno, Sakiyo Tsukamoto, Ryo Fujii, Akihiro Ohashi, Yutaka Suzuki, Katsuya Tsuchihara, Hiroyoshi Nishikawa, Toshihiko Doi
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79385-w

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