Immunohistochemical study of enteric nervous system in dexamethasone-treated rats
The gut is supplied with its own nervous system, referred to as the enteric nervous system (ENS). It regulates the various functions of a digestive system such as motility, secretion and digestion and has close interactions with the enteric immune system. The aim of this study was to investigate the...
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University of Kragujevac, Faculty of Science
2018-01-01
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doaj-ed5bae6082914c6d810580a6fe9649b02020-11-25T00:44:09ZengUniversity of Kragujevac, Faculty of ScienceKragujevac Journal of Science1450-96362466-55092018-01-012018401631731450-96361840163GImmunohistochemical study of enteric nervous system in dexamethasone-treated ratsGlišić Radmila M.0Čakić-Milošević Maja M.1Ukropina Mirela M.2University of Kragujevac, Faculty of Science, Department of Biology and Ecology, KragujevacUniversity of Belgrade, Faculty of Biology, Institute of Zoology, BelgradeUniversity of Belgrade, Faculty of Biology, Institute of Zoology, BelgradeThe gut is supplied with its own nervous system, referred to as the enteric nervous system (ENS). It regulates the various functions of a digestive system such as motility, secretion and digestion and has close interactions with the enteric immune system. The aim of this study was to investigate the alterations of the ENS in dexamethasone-treated rats using two general neuroendocrine markers: protein gene product 9.5 (PGP 9.5) and synaptophysin (SY). As concluded from the changes in a pattern of immunoexpression of the markers applied, some remodeling of the ENS occured. Further investigations are needed to elucidate in more details its nature and importance with respect to gastrointestinal complications seen in diabetes.https://scindeks-clanci.ceon.rs/data/pdf/1450-9636/2018/1450-96361840163G.pdfenteric nervous systemdexamethasonerat |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Glišić Radmila M. Čakić-Milošević Maja M. Ukropina Mirela M. |
spellingShingle |
Glišić Radmila M. Čakić-Milošević Maja M. Ukropina Mirela M. Immunohistochemical study of enteric nervous system in dexamethasone-treated rats Kragujevac Journal of Science enteric nervous system dexamethasone rat |
author_facet |
Glišić Radmila M. Čakić-Milošević Maja M. Ukropina Mirela M. |
author_sort |
Glišić Radmila M. |
title |
Immunohistochemical study of enteric nervous system in dexamethasone-treated rats |
title_short |
Immunohistochemical study of enteric nervous system in dexamethasone-treated rats |
title_full |
Immunohistochemical study of enteric nervous system in dexamethasone-treated rats |
title_fullStr |
Immunohistochemical study of enteric nervous system in dexamethasone-treated rats |
title_full_unstemmed |
Immunohistochemical study of enteric nervous system in dexamethasone-treated rats |
title_sort |
immunohistochemical study of enteric nervous system in dexamethasone-treated rats |
publisher |
University of Kragujevac, Faculty of Science |
series |
Kragujevac Journal of Science |
issn |
1450-9636 2466-5509 |
publishDate |
2018-01-01 |
description |
The gut is supplied with its own nervous system, referred to as the enteric nervous system (ENS). It regulates the various functions of a digestive system such as motility, secretion and digestion and has close interactions with the enteric immune system. The aim of this study was to investigate the alterations of the ENS in dexamethasone-treated rats using two general neuroendocrine markers: protein gene product 9.5 (PGP 9.5) and synaptophysin (SY). As concluded from the changes in a pattern of immunoexpression of the markers applied, some remodeling of the ENS occured. Further investigations are needed to elucidate in more details its nature and importance with respect to gastrointestinal complications seen in diabetes. |
topic |
enteric nervous system dexamethasone rat |
url |
https://scindeks-clanci.ceon.rs/data/pdf/1450-9636/2018/1450-96361840163G.pdf |
work_keys_str_mv |
AT glisicradmilam immunohistochemicalstudyofentericnervoussystemindexamethasonetreatedrats AT cakicmilosevicmajam immunohistochemicalstudyofentericnervoussystemindexamethasonetreatedrats AT ukropinamirelam immunohistochemicalstudyofentericnervoussystemindexamethasonetreatedrats |
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1725276106378969088 |