Temporal and spatial transcriptional fingerprints by antipsychotic or propsychotic drugs in mouse brain.

Various types of antipsychotics have been developed for the treatment of schizophrenia since the accidental discovery of the antipsychotic activity of chlorpromazine. Although all clinically effective antipsychotic agents have common properties to interact with the dopamine D2 receptor (D2R) activat...

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Bibliographic Details
Main Authors: Kensuke Sakuma, Hidetoshi Komatsu, Minoru Maruyama, Sachiko Imaichi, Yugo Habata, Masaaki Mori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4334909?pdf=render