Melatonin Plays a Critical Protective Role in Nicotine-Related Abdominal Aortic Aneurysm

Melatonin Plays a Critical Protective Role in Nicotine-Related Abdominal Aortic Aneurysm

Aim: Smoking is a major risk factor for abdominal aortic aneurysm (AAA). Among the components of smoke, nicotine is known to exert pro-atherosclerotic, prothrombotic, and proangiogenic effects on vascular smooth muscle cells (VSMCs). The current study was designed to investigate the mechanisms throu...

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Bibliographic Details
Main Authors: Liren Duan, Shenli Li, Lei Wang, Yuchen Jing, Guangxin Li, Yaodong Sun, Weifeng Sun, Yalun Li, Lin Zhao, Shijie Xin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
melatonin
nicotine
abdominal aortic aneurysm
vascular smooth muscle cell
phenotypic switch
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00866/full

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