Active immunization trial in Aβ42-injected P301L tau transgenic mice

Active immunization trial in Aβ42-injected P301L tau transgenic mice

Amyloid β-peptide (Aβ) containing plaques and neurofibrillary tangles (NFT) are the two major histopathological hallmarks of Alzheimer's disease (AD). According to the amyloid cascade hypothesis, deposition of Aβ is an initial and essential step in the pathogenesis of AD, and formation of NFT h...

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Bibliographic Details
Main Authors:	Luka Kulic, Pascal Kurosinski, Feng Chen, Jay Tracy, M. Hasan Mohajeri, Hong Li, Roger M. Nitsch, Jürgen Götz
Format:	Article
Language:	English
Published:	Elsevier 2006-04-01
Series:	Neurobiology of Disease
Subjects:	Alzheimer's disease Brain Vaccination Amyloid β-peptide Tau Transgenic
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996105002718

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