Two to Tango: Co-evolution of Hominid Natural Killer Cell Receptors and MHC

Two to Tango: Co-evolution of Hominid Natural Killer Cell Receptors and MHC

Natural killer (NK) cells have diverse roles in hominid immunity and reproduction. Modulating these functions are the interactions between major histocompatibility complex (MHC) class I molecules that are ligands for two NK cell surface receptor types. Diverse killer cell immunoglobulin-like recepto...

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Bibliographic Details
Main Authors: Emily E. Wroblewski, Peter Parham, Lisbeth A. Guethlein
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
NK cells
MHC
KIR
CD94
NKG2
hominid
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00177/full

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