Research priorities during infectious disease emergencies in West Africa
Abstract Objectives This paper presents the results of the consultations conducted with various stakeholders in Africa and other experts to document community perspectives on the types of research to be prioritised in outbreak conditions. The Delphi method was used to distill consensus. Results Our...
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doaj-edab7c005a1f4c8f8d28f91643b530812020-11-25T02:37:14ZengBMCBMC Research Notes1756-05002018-03-011111510.1186/s13104-018-3263-3Research priorities during infectious disease emergencies in West AfricaMorenike Oluwatoyin Folayan0Bridget Haire1Dan Allman2Aminu Yakubu3Muhammed O. Afolabi4Institute of Public Health, Obafemi Awolowo UniversityKirby Institute, University of New South WalesDalla Lana School of Public Health, University of TorontoFederal Ministry of HealthDepartment of Clinical Research, London School of Hygiene & Tropical MedicineAbstract Objectives This paper presents the results of the consultations conducted with various stakeholders in Africa and other experts to document community perspectives on the types of research to be prioritised in outbreak conditions. The Delphi method was used to distill consensus. Results Our consultations highlighted as key, the notion that in an infectious disease outbreak situation, the need to establish an evidence base on how to reduce morbidity and mortality in real time takes precedence over the production of generalizable knowledge. Research studies that foster understanding of how disease transmission could be prevented in the future remain important, implementation research that explores how to mitigate the impact of outbreaks in the present should be prioritized. Clinical trials aiming to establish the safety profile of therapeutic interventions should be limited during the acute phase of an epidemic with high fatality—and should preferably use adaptive designs. We concluded that community members have valuable perspectives to share about research priorities during infectious disease emergencies. Well designed consultative processes could help identify these opinions.http://link.springer.com/article/10.1186/s13104-018-3263-3Infectious diseaseEpidemicWest AfricaResearch prioritiesResearch designConsultation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Morenike Oluwatoyin Folayan Bridget Haire Dan Allman Aminu Yakubu Muhammed O. Afolabi |
spellingShingle |
Morenike Oluwatoyin Folayan Bridget Haire Dan Allman Aminu Yakubu Muhammed O. Afolabi Research priorities during infectious disease emergencies in West Africa BMC Research Notes Infectious disease Epidemic West Africa Research priorities Research design Consultation |
author_facet |
Morenike Oluwatoyin Folayan Bridget Haire Dan Allman Aminu Yakubu Muhammed O. Afolabi |
author_sort |
Morenike Oluwatoyin Folayan |
title |
Research priorities during infectious disease emergencies in West Africa |
title_short |
Research priorities during infectious disease emergencies in West Africa |
title_full |
Research priorities during infectious disease emergencies in West Africa |
title_fullStr |
Research priorities during infectious disease emergencies in West Africa |
title_full_unstemmed |
Research priorities during infectious disease emergencies in West Africa |
title_sort |
research priorities during infectious disease emergencies in west africa |
publisher |
BMC |
series |
BMC Research Notes |
issn |
1756-0500 |
publishDate |
2018-03-01 |
description |
Abstract Objectives This paper presents the results of the consultations conducted with various stakeholders in Africa and other experts to document community perspectives on the types of research to be prioritised in outbreak conditions. The Delphi method was used to distill consensus. Results Our consultations highlighted as key, the notion that in an infectious disease outbreak situation, the need to establish an evidence base on how to reduce morbidity and mortality in real time takes precedence over the production of generalizable knowledge. Research studies that foster understanding of how disease transmission could be prevented in the future remain important, implementation research that explores how to mitigate the impact of outbreaks in the present should be prioritized. Clinical trials aiming to establish the safety profile of therapeutic interventions should be limited during the acute phase of an epidemic with high fatality—and should preferably use adaptive designs. We concluded that community members have valuable perspectives to share about research priorities during infectious disease emergencies. Well designed consultative processes could help identify these opinions. |
topic |
Infectious disease Epidemic West Africa Research priorities Research design Consultation |
url |
http://link.springer.com/article/10.1186/s13104-018-3263-3 |
work_keys_str_mv |
AT morenikeoluwatoyinfolayan researchprioritiesduringinfectiousdiseaseemergenciesinwestafrica AT bridgethaire researchprioritiesduringinfectiousdiseaseemergenciesinwestafrica AT danallman researchprioritiesduringinfectiousdiseaseemergenciesinwestafrica AT aminuyakubu researchprioritiesduringinfectiousdiseaseemergenciesinwestafrica AT muhammedoafolabi researchprioritiesduringinfectiousdiseaseemergenciesinwestafrica |
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1724795983567519744 |