Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG Analyser
Introduction: The introduction of a new method or new analyser is a common occurrence in clinical biochemistry laboratory. Blood gas measurements and electrolytes are often performed in Point-of-Care (POC) settings. When a new POC analyser is obtained, the performance of the analyser should be e...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Private Limited
2014-06-01
|
Series: | Journal of Clinical and Diagnostic Research |
Subjects: | |
Online Access: | https://jcdr.net/articles/PDF/4442/9218_CE(Ra1)_F(H)_PF1(AGAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdf |
Summary: | Introduction: The introduction of a new method or new analyser
is a common occurrence in clinical biochemistry laboratory.
Blood gas measurements and electrolytes are often performed
in Point-of-Care (POC) settings. When a new POC analyser is
obtained, the performance of the analyser should be evaluated
by comparison to the measurements with the reference analyser
in the laboratory.
Objectives: Evaluation of method performance of pH, PCO2
,
PO2
, Na+, K+ of cobas b121 ABG analyser.
Materials & Methods: The evaluation of method performance
of pH, PO2
, PCO2
, Na+, K+ of cobas b121 ABG analyser was
done by comparing the results of 50 patient samples run on
cobas b121 with the results obtained from Rapid lab values
(reference analyser). Correlation coefficient was calculated from
the results obtained from both the analysers. Precision was
calculated by running biorad ABG control samples.
Results: The correlation coefficient values obtained for
parameters were close to 1.0 indicating good correlation. The
CV obtained for all the parameters were less than 5 indicating
good precision.
Conclusion: The new ABG analyser, Cobas b121 correlated
well with the reference ABG analyser (Rapid Lab) and could be
used to run on patient samples. |
---|---|
ISSN: | 2249-782X 0973-709X |