Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG Analyser
Introduction: The introduction of a new method or new analyser is a common occurrence in clinical biochemistry laboratory. Blood gas measurements and electrolytes are often performed in Point-of-Care (POC) settings. When a new POC analyser is obtained, the performance of the analyser should be e...
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doaj-edc6765f90374ec8a6871fcf339cca172020-11-25T03:13:21ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-06-0186CC05CC0710.7860/JCDR/2014/9218.4442Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG AnalyserSunil Kumar Nanda0Lopamudra Ray1Asha Dinakaran2Associate Professor, Department of Biochemistry, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Ganapathichettikulam, Kalapet, Pondicherry, India.Assistant Professor, Department of Biochemistry, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Ganapathichettikulam, Kalapet, Pondicherry, India.Tutor, Department of Biochemistry, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Ganapathichettikulam, Kalapet, Pondicherry, India.Introduction: The introduction of a new method or new analyser is a common occurrence in clinical biochemistry laboratory. Blood gas measurements and electrolytes are often performed in Point-of-Care (POC) settings. When a new POC analyser is obtained, the performance of the analyser should be evaluated by comparison to the measurements with the reference analyser in the laboratory. Objectives: Evaluation of method performance of pH, PCO2 , PO2 , Na+, K+ of cobas b121 ABG analyser. Materials & Methods: The evaluation of method performance of pH, PO2 , PCO2 , Na+, K+ of cobas b121 ABG analyser was done by comparing the results of 50 patient samples run on cobas b121 with the results obtained from Rapid lab values (reference analyser). Correlation coefficient was calculated from the results obtained from both the analysers. Precision was calculated by running biorad ABG control samples. Results: The correlation coefficient values obtained for parameters were close to 1.0 indicating good correlation. The CV obtained for all the parameters were less than 5 indicating good precision. Conclusion: The new ABG analyser, Cobas b121 correlated well with the reference ABG analyser (Rapid Lab) and could be used to run on patient samples.https://jcdr.net/articles/PDF/4442/9218_CE(Ra1)_F(H)_PF1(AGAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdfblood gaselectrolytespoint of care |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sunil Kumar Nanda Lopamudra Ray Asha Dinakaran |
spellingShingle |
Sunil Kumar Nanda Lopamudra Ray Asha Dinakaran Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG Analyser Journal of Clinical and Diagnostic Research blood gas electrolytes point of care |
author_facet |
Sunil Kumar Nanda Lopamudra Ray Asha Dinakaran |
author_sort |
Sunil Kumar Nanda |
title |
Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG Analyser |
title_short |
Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG Analyser |
title_full |
Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG Analyser |
title_fullStr |
Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG Analyser |
title_full_unstemmed |
Validation of Method Performance of pH, PCO2 , PO2 , Na+, K+ of Cobas b121 ABG Analyser |
title_sort |
validation of method performance of ph, pco2 , po2 , na+, k+ of cobas b121 abg analyser |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2014-06-01 |
description |
Introduction: The introduction of a new method or new analyser
is a common occurrence in clinical biochemistry laboratory.
Blood gas measurements and electrolytes are often performed
in Point-of-Care (POC) settings. When a new POC analyser is
obtained, the performance of the analyser should be evaluated
by comparison to the measurements with the reference analyser
in the laboratory.
Objectives: Evaluation of method performance of pH, PCO2
,
PO2
, Na+, K+ of cobas b121 ABG analyser.
Materials & Methods: The evaluation of method performance
of pH, PO2
, PCO2
, Na+, K+ of cobas b121 ABG analyser was
done by comparing the results of 50 patient samples run on
cobas b121 with the results obtained from Rapid lab values
(reference analyser). Correlation coefficient was calculated from
the results obtained from both the analysers. Precision was
calculated by running biorad ABG control samples.
Results: The correlation coefficient values obtained for
parameters were close to 1.0 indicating good correlation. The
CV obtained for all the parameters were less than 5 indicating
good precision.
Conclusion: The new ABG analyser, Cobas b121 correlated
well with the reference ABG analyser (Rapid Lab) and could be
used to run on patient samples. |
topic |
blood gas electrolytes point of care |
url |
https://jcdr.net/articles/PDF/4442/9218_CE(Ra1)_F(H)_PF1(AGAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdf |
work_keys_str_mv |
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