Data set on a study of gene expression in peripheral samples to identify biomarkers of severity of allergic and nonallergic asthma

• Main Authors: Selene Baos, David Calzada, Lucía Cremades, Joaquín Sastre, Joaquín Quiralte, Fernando Florido, Carlos Lahoz, Blanca Cárdaba
• Format: Article
• Language: English
• Published: Elsevier 2017-02-01
• Series: Data in Brief
• Subjects: Asthma; Allergy; Biomarkers; Gene expression; Peripheral samples
• Online Access: http://www.sciencedirect.com/science/article/pii/S235234091630796X

This article contains information related to the research article entitled “Biomarkers associated with disease severity in allergic and nonallergic asthma” (S. Baos, D. Calzada, L. Cremades, J. Sastre, J. Quiralte, F. Florido, C. Lahoz, B. Cárdaba, In press). Specifically, the clinical criteria stablished for selecting the study population (n=104 subjects) are described. Moreover, this article describes the criteria for selecting the 94 genes to be analyzed in PBMCs (peripheral blood mononuclear cells), it is provided a description of these genes and a Table with the genes most differentially expressed by clinical phenotypes and, finally it is detailed the experimental methodology followed for studying the protein expression of MSR1 (macrophage scavenger receptor 1), one of the genes evaluated in the research.