Exogenous R-Spondin1 Induces Precocious Telogen-to-Anagen Transition in Mouse Hair Follicles

Exogenous R-Spondin1 Induces Precocious Telogen-to-Anagen Transition in Mouse Hair Follicles

R-spondin proteins are novel Wnt/β-catenin agonists, which signal through their receptors leucine-rich repeat-containing G-protein coupled receptor (LGR) 4/5/6 and substantially enhance Wnt/β-catenin activity. R-spondins are reported to function in embryonic development. They also play important rol...

Full description

Bibliographic Details
Main Authors: Na Li, Shu Liu, Hui-Shan Zhang, Zhi-Li Deng, Hua-Shan Zhao, Qian Zhao, Xiao-Hua Lei, Li-Na Ning, Yu-Jing Cao, Hai-Bin Wang, Shuang Liu, En-Kui Duan
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:International Journal of Molecular Sciences
Subjects:
R-spondin
Wnt/β-catenin
hair follicle stem cells
hair cycle
Online Access:http://www.mdpi.com/1422-0067/17/4/582

Internet

http://www.mdpi.com/1422-0067/17/4/582

Similar Items