Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion

Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion

Abstract Background The migration of peripheral immune cells and splenocytes to the ischemic brain is one of the major causes of delayed neuroinflammation after permanent large vessel stroke. Other groups have demonstrated that leukemia inhibitory factor (LIF), a cytokine that promotes neural cell s...

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Bibliographic Details
Main Authors: Stephanie M. Davis, Lisa A. Collier, Edric D. Winford, Christopher C. Leonardo, Craig T. Ajmo, Elspeth A. Foran, Timothy J. Kopper, John C. Gensel, Keith R. Pennypacker
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Neuroinflammation
Subjects:
Stroke
Inflammation
Macrophages
Ischemia
Cytokines
Online Access:http://link.springer.com/article/10.1186/s12974-018-1326-y

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