Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS
According to the GC-MS analysis, compositional variation was observed between samples of patchouli oil, of which an unknown compound identified as patchoulene epoxide (PAO) was found only in the long-stored oil, whose biological activity still remains unknown. Therefore, the present study aimed to e...
Main Authors: | Jia-Li Liang, Jia-Zhen Wu, Yu-Hong Liu, Zhen-Biao Zhang, Qi-Duan Wu, Han-Bin Chen, Yan-Feng Huang, Yao-Xing Dou, Jiang-Tao Zhou, Zi-Ren Su, Janis Ya-Xian Zhan |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2017/1089028 |
Similar Items
-
Comparison of anti-inflammatory effect between β-patchoulene epoxide and β-patchoulene in LPS-stimulated RAW264.7 macrophages
by: Xue Wu, et al.
Published: (2018-06-01) -
Transformation of patchouli alcohol to β-patchoulene by gastric juice: β-patchoulene is more effective in preventing ethanol-induced gastric injury
by: Yuhong Liu, et al.
Published: (2017-07-01) -
β-Patchoulene, isolated from patchouli oil, suppresses inflammatory mediators in LPS-stimulated RAW264.7 macrophages
by: Wen-Hao Yang, et al.
Published: (2017-08-01) -
Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-κB signaling pathways
by: Ching-Shu Lai, et al.
Published: (2011-07-01) -
Oleic acid ameliorates Aβ-induced inflammation by downregulation of COX-2 and iNOS via NFκB signaling pathway
by: Hyeri Kim, et al.
Published: (2015-04-01)