PGAM5 expression and macrophage signatures in non-small cell lung cancer associated with chronic obstructive pulmonary disease (COPD)

PGAM5 expression and macrophage signatures in non-small cell lung cancer associated with chronic obstructive pulmonary disease (COPD)

Abstract Background COPD patients are at increased risk of developing non-small cell lung carcinoma that has a worse prognosis. Oxidative stress contributes to carcinogenesis and is increased in COPD patients due to mitochondrial dysfunction. We determined whether mitochondrial dysfunction is a cont...

Full description

Bibliographic Details
Main Authors: F. Ng Kee Kwong, A. G. Nicholson, S. Pavlidis, I. M. Adcock, K. F. Chung
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Mitochondrion
Lung cancer
PGAM5 macrophage
Patient survival
Online Access:http://link.springer.com/article/10.1186/s12885-018-5140-9

Similar Items

Similar Items