Research progress of miRNA and siRNA in spinocerebellar ataxia type 3

Research progress of miRNA and siRNA in spinocerebellar ataxia type 3

Spinocerebellar ataxia type 3 (SCA3) is a type of polyglutamine (polyQ) disease with expansion mutant ATXN3 gene as its causative gene which contains cytosine-adenine-guanine (CAG) repeat sequence at the coding region of 3-terminal. The polyQ expansion mutant ATXN3 gene encoded polyQ expansion mutan...

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Bibliographic Details
Main Authors: Feng-zhen HUANG, Xuan HOU, Bei-sha TANG, Hong JIANG
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2013-08-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
MicroRNAs
RNA, small interfering
Machado-Joseph disease
Trinucleotide repeats
Review
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/791

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