Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner.

Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner.

Rho kinases (ROCKs) mediate cell contraction, local adhesion, and cell motility, which are considered to be important in cell differentiation. We postulated that ROCKs are involved in controlling embryonic stem (ES) cell renewal and differentiation.CCE, a murine ES cell, was treated with Y-27632 for...

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Bibliographic Details
Main Authors: Tzu-Ching Chang, Yen-Chung Chen, Ming-Hua Yang, Chien-Hung Chen, En-Wei Hsing, Bor-Sheng Ko, Jun-Yang Liou, Kenneth K Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2820554?pdf=render

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http://europepmc.org/articles/PMC2820554?pdf=render

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