PPARγ agonists promote oligodendrocyte differentiation of neural stem cells by modulating stemness and differentiation genes.
Neural stem cells (NSCs) are a small population of resident cells that can grow, migrate and differentiate into neuro-glial cells in the central nervous system (CNS). Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor transcription factor that regulates cell growth and di...
Main Authors: | Saravanan Kanakasabai, Ecaterina Pestereva, Wanida Chearwae, Sushil K Gupta, Saif Ansari, John J Bright |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3503969?pdf=render |
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