Design principles of collateral sensitivity-based dosing strategies
Collateral sensitivity-based antibiotic treatments may have the potential to limit the emergence of antimicrobial resistance. Here, the authors use mathematical modelling to study the effects of pathogen- and drug-specific characteristics for different treatment designs on bacterial population dynam...
Main Authors: | Linda B. S. Aulin, Apostolos Liakopoulos, Piet H. van der Graaf, Daniel E. Rozen, J. G. Coen van Hasselt |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-25927-3 |
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